18:24 , Aug 31, 2018 |  BC Week In Review  |  Clinical News

Kyowa's KW-6356 improves motor symptoms in Phase IIa for early PD

Kyowa Hakko Kirin Co. Ltd. (Tokyo:4151) said low- and high-dose oral KW-6356 both improved motor symptoms compared with placebo in a Phase IIa trial in 168 patients with early Parkinson's disease who had not received...
06:27 , Aug 10, 2018 |  BC Week In Review  |  Company News

China Medical gains rights to Can-Fite's ADORA3 agonists

CMS Medical Venture Investment Ltd. gained rights to develop and commercialize piclidenoson (CF101) and namodenoson (CF102) in Taiwan and China, including Hong Kong and Macau, from Can-Fite BioPharma Ltd. (Tel Aviv:CFBI; NYSE-A:CANF). Can-Fite received $2 million...
16:14 , Jul 20, 2018 |  BC Week In Review  |  Company News

Taiho exercises option for AB928

Taiho Pharmaceutical Co. Ltd. (Tokyo, Japan) exercised an option to develop and commercialize AB928 from cancer company Arcus Biosciences Inc. (NYSE:RCUS) in Japan and other Asian territories, excluding China. Arcus will receive an option exercise payment...
19:01 , Jun 22, 2018 |  BC Week In Review  |  Financial News

Oncology play iTeos raises $75M, outlines clinical plans

iTeos Therapeutics S.A. (Gosselies, Belgium) raised $75 million on June 19 in a series B round led by MPM Capital. Also participating in the round were HBM Partners, 6 Dimensions Capital, Curative Ventures and SFPI as...
19:04 , Jun 20, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Staphylococcus Cell culture studies suggest inhibiting adenosine kinase, DCK or SLC29A1 could help treat Staphylococcus aureus infection. Screening of a CRISPR single-guide RNA (sgRNA) library in a human lung lymphoblast cell line expressing CRISPR-associated protein...
01:47 , Jun 20, 2018 |  BC Extra  |  Financial News

Oncology play iTeos raises $75M, outlines clinical plans

iTeos Therapeutics S.A. (Gosselies, Belgium) raised $75 million in a series B round led by MPM Capital. Also participating in the round were HBM Partners, 6 Dimensions Capital, Curative Ventures and SFPI as well as...
01:38 , Jun 20, 2018 |  BioCentury  |  Finance

Iterating iTeos

With a new office in the U.S. and $75 million in fresh series B funding to support clinical development of at least two candidates, Belgian cancer company iTeos Therapeutics S.A. is considering a U.S. IPO...
21:50 , Jun 14, 2018 |  BC Innovations  |  Emerging Company Profile

Beaming about base changes

Beam Therapeutics launched with a CRISPR-guided base editor platform that could introduce more precise point mutations than other gene editing technologies without the risk of off-target cuts. Founded by CRISPR veterans David Liu of Harvard University,...
18:26 , Jun 13, 2018 |  BC Innovations  |  Distillery Techniques

Other

TECHNOLOGY: Computational models A method for designing small molecules that bind two protein targets could be used to generate dual inhibitors. The method utilizes in silico docking of a library of drug-like compounds and compound fragments...
05:50 , Jun 2, 2018 |  BioCentury  |  Product Development

Breaking from the herd

Behind the block of clinical studies on PD-1 and PD-L1 inhibitors, researchers are casting aside their herd mentality with a wide net of strategies to solve some of the most pressing problems in oncology, such...