07:00 , May 15, 2014 |  BC Innovations  |  Cover Story

Chromatin's rising tide

To capitalize on the full range of possible chromatin targets in and beyond oncology, industry and academia will need to delve deeper into how chromatin regulation is altered in disease, create tools that can reliably...
08:00 , Jan 27, 2014 |  BioCentury  |  Emerging Company Profile

Salarius: Kicking LSD

Salarius Pharmaceuticals LLC is using a fragment-based discovery approach to develop safer inhibitors of lysine-specific histone demethylase, an epigenetic target that is up-regulated in hormone-dependent cancers and essential in specific forms of acute myelogenous leukemia...