18:01 , Oct 25, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Seizures Fruit fly studies suggest inhibiting FAK, integrin β, TLN1, TNS1 or MMP1 could help treat seizures. In a...
07:00 , Sep 4, 2014 |  BC Innovations  |  Distillery Therapeutics

Indication: Cancer

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer Cancer Focal adhesion kinase (FAK) Mouse studies suggest endothelial cell-specific inhibition of FAK could help sensitize tumors to chemotherapy. In mouse models of melanoma and...
07:00 , Apr 10, 2014 |  BC Innovations  |  Cover Story

Pre-EMP-tive strike against GBM

University of California, Los Angeles researchers have treated glioblastoma in mice by inhibiting epithelial membrane protein 2 . 1 The findings open up a new indication for spinout Paganini Biopharma Inc. , which has a...
08:00 , Dec 10, 2012 |  BC Week In Review  |  Clinical News

GSK2256098: Phase I data

An open-label, international Phase I trial in 29 patients with recurrent mesothelioma showed that twice-daily oral GSK2256098 produced 14 cases of stable disease. Median progression-free survival (PFS) was 17.7 weeks. In patients with neurofibromin 2...