A key challenge in mining the microbiome for therapeutic strategies has been to characterize the functional role of specific bacterial populations in the context of a disease. Now, University of California researchers have shown the...

Indication Target/marker/pathway Summary Licensing status Publication and contact information Cancer B cell lymphoma Unknown Mouse studies suggest Lactobacillus johnsonii supplementation could help prevent ataxia-telangiectasia−associated B cell lymphomas. In a mouse model of ataxia telangiectasia, mice...

Approach Summary Licensing status Publication and contact information Assays & screens Culture of human pluripotent stem (hPS) cells in non-muscle myosin II (MYH10; NMHCII)-depleted conditions to improve viability and increase available cells for clinical applications...

Development of malaria therapeutics has been stymied by poor understanding of drug targets and limited corporate interest in picking up preclinical compounds with therapeutic promise. At the same time, the parasite has shown mounting resistance...

This week in therapeutics Indication Target/ marker/pathway Summary Licensing status Publication and contact information Infectious disease Malaria Proteasome An in vitro screening study suggests that the proteasome inhibitor salinosporamide A could be used to treat...

Alydar Pharmaceuticals Inc. , Mountain View, Calif. Business: Cardiovascular, Neurological, Cancer Appointed: Thomas Eisner, professor of chemical ecology at Cornell University; Jerrold Meinwald, professor of chemistry at Cornell University; and Jocelyn Millar, professor of entomology at...