21:50 , May 7, 2019 |  BC Extra  |  Tools & Techniques

Imaging data boosts accuracy of 3-D chromosome models

The latest advance in mapping 3-D genomic structures has improved modeling by integrating an imaging technique with sequencing technology. 3-D chromatin architectures, which help regulate gene expression, are emerging targets for cancer and developmental disorders....
12:57 , Apr 30, 2019 |  BC Innovations  |  Distillery Therapeutics

The Parkinson's drug Comtam for obesity and diabetes

DISEASE CATEGORY: Endocrine/metabolic INDICATION: Obesity; diabetes In silico and mouse studies identified Comtan entacapone as an FTO inhibitor that could help treat obesity and diabetes. An in silico screen of FDA-approved drugs for FTO binding...
18:19 , Dec 7, 2018 |  BC Week In Review  |  Company News

Brii expands in infectious via deals with Vir, VBI, WuXi Biologics

Brii Biosciences (Shanghai, China) is broadening its pipeline in HBV and other infectious diseases through a series of new and expanded deals announced Dec. 6, even as CEO Zhi Hong said the company is looking...
13:00 , Dec 6, 2018 |  BC Extra  |  Company News

Brii expands in infectious via deals with Vir, VBI, WuXi Biologics

Brii Biosciences (Shanghai, China) is broadening its pipeline in HBV and other infectious diseases through a series of new and expanded deals announced Thursday, even as CEO Zhi Hong said the company is looking to...
00:55 , Nov 27, 2018 |  BC Extra  |  Preclinical News

Chinese researchers rebuke scientist for CRISPR babies; a ‘huge blow’ to country’s reputation

More than 100 Chinese researchers condemned as a “huge blow to the global reputation and development” of Chinese research the use of CRISPR to genetically modify two human babies. In an open letter , 124...
20:24 , Oct 31, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer; infectious disease

INDICATION: Cancer; melanoma; cervical cancer; influenza virus Mouse and monkey studies suggest simvastatin could be used as an adjuvant to boost the efficacy of cancer and influenza vaccines. In mice, immunization with the antigen ovalbumin...
18:08 , Sep 7, 2018 |  BC Week In Review  |  Company News

Boehringer partners with Chinese university for infectious disease therapies

Boehringer Ingelheim GmbH (Ingelheim, Germany) and Tsinghua University (Beijing, China) partnered to research and develop therapies for infectious diseases using immune modulation. The Tsinghua deal is part of Boehringer's Research Beyond Borders (RBB) program, designed...
18:28 , Aug 31, 2018 |  BC Week In Review  |  Financial News

Sequoia China leads seed round for next-gen T cell therapy play

RootPath Inc. (Cambridge, Mass.) raised on Aug. 30 $7 million in a seed round led by Sequoia China. Fellow new investors Volcanics Venture, Baidu Ventures and Nest.Bio Ventures also participated. Co-founder and CEO Xi Chen...
11:00 , Aug 30, 2018 |  BC Extra  |  Financial News

Sequoia China leads seed round for next-gen T cell therapy play

RootPath Inc. (Cambridge, Mass.) raised $7 million in a seed round led by Sequoia China. Fellow new investors Volcanics Venture, Baidu Ventures and Nest.Bio Ventures also participated. Co-founder and CEO Xi Chen told BioCentury the...
18:43 , Jul 27, 2018 |  BC Week In Review  |  Company News

BMS expands R&D collaboration with Tsinghua

Bristol-Myers Squibb Co. (NYSE:BMY) and Tsinghua University expanded a 2012 deal to include identification and validation of new targets in autoimmune diseases and cancer, as well as for discovery of candidates for clinical development. BMS...