BioCentury | Sep 12, 2019
Distillery Therapeutics

Preventing metastasis in TNBC with liposome-delivered TRAIL

DISEASE CATEGORY: Cancer INDICATION: Breast Cancer Liposomes formulated to display the apoptosis inducer TRAIL and the tumor-binding adhesion molecule SELE could treat triple-negative breast cancer (TNBC) and prevent metastases following tumor resection. When administered to...
BioCentury | Aug 6, 2019
Company News

Management tracks: Allogene snags Adaptimmune's Amado; plus Foundation Medicine, CymaBay and more

...Pharmaceuticals Ltd. (Jerusalem, Israel) co-founder, CSO and CEO Alberto Gabizon will also become president of the liposome...
BioCentury | Apr 2, 2019
Distillery Techniques

Dual-targeting liposomes for cancer therapy delivery

TECHNIQUES CATEGORY: Drug delivery TECHNOLOGY: Nanoparticles Dual-targeting liposomes could be used to deliver cancer therapies. Generation of the liposomes involves two steps: screening human cancer cell lines against a 68-gene panel of common cancer targets...
BioCentury | Jun 28, 2018
Distillery Therapeutics

Cancer

INDICATION: Brain cancer Mouse studies suggest transferrin-conjugated liposomal nanoparticles loaded with temozolomide and an inhibitor of BET bromodomain proteins could help treat glioma. The liposomal nanoparticles contain distearoylglycerophosphoethanolamine (DSPE) conjugated to polyethylene glycol (PEG) and...
BioCentury | May 23, 2018
Distillery Therapeutics

Cancer

INDICATION: Breast cancer; brain cancer; solid tumors Mouse studies suggest liposomal nanoparticles loaded with immunomodulatory agents could enhance the efficacy of CAR T therapies to treat solid cancers. The liposomal nanoparticles are coated with an...
BioCentury | Apr 4, 2018
Politics & Policy

CDER releases guidance on liposome products

...that are specific to the liposome's structure and integrity, as those properties reflect the ability of the liposome...
BioCentury | Dec 5, 2017
Distillery Techniques

Assays and screens

TECHNOLOGY: Cell-free assays; diagnostic assays An assay for detecting GPC1 mRNA in serum extracellular vesicles could help diagnose PDAC. The assay involves adding patient serum samples to a slide coated with cationic liposomes loaded with...
BioCentury | Oct 10, 2017
Distillery Therapeutics

Inflammation

INDICATION: Inflammation Cell culture and mouse studies suggest photosynthetic hydrogen-generating liposomes could help treat inflammation. The liposomes were loaded with three components: the red light photosensitizer chlorophyll a ; the proton donor ascorbic acid; and...
BioCentury | Jun 27, 2017
Distillery Techniques

Drug delivery

TECHNOLOGY: Nanoparticles Estrone-conjugated liposomes could be used to deliver therapies to ESR1 -positive tumors. The liposomes are composed of distearoylglycerophosphoethanolamine (DSPE) conjugated to polyethylene glycol (PEG) and the ESR1 ligand estrone and loaded with a...
BioCentury | May 4, 2017
Clinical News

FDA grants TLC178 rare pediatric disease designation

FDA granted rare pediatric disease designation to TLC178 from Taiwan Liposome Co. Ltd. (TPEx:4152) to treat rhabdomyosarcoma. The liposomal encapsulated formulation of vinorelbine has Orphan Drug designation from FDA to treat cutaneous T cell lymphoma...
Items per page:
1 - 10 of 335
BioCentury | Sep 12, 2019
Distillery Therapeutics

Preventing metastasis in TNBC with liposome-delivered TRAIL

DISEASE CATEGORY: Cancer INDICATION: Breast Cancer Liposomes formulated to display the apoptosis inducer TRAIL and the tumor-binding adhesion molecule SELE could treat triple-negative breast cancer (TNBC) and prevent metastases following tumor resection. When administered to...
BioCentury | Aug 6, 2019
Company News

Management tracks: Allogene snags Adaptimmune's Amado; plus Foundation Medicine, CymaBay and more

...Pharmaceuticals Ltd. (Jerusalem, Israel) co-founder, CSO and CEO Alberto Gabizon will also become president of the liposome...
BioCentury | Apr 2, 2019
Distillery Techniques

Dual-targeting liposomes for cancer therapy delivery

TECHNIQUES CATEGORY: Drug delivery TECHNOLOGY: Nanoparticles Dual-targeting liposomes could be used to deliver cancer therapies. Generation of the liposomes involves two steps: screening human cancer cell lines against a 68-gene panel of common cancer targets...
BioCentury | Jun 28, 2018
Distillery Therapeutics

Cancer

INDICATION: Brain cancer Mouse studies suggest transferrin-conjugated liposomal nanoparticles loaded with temozolomide and an inhibitor of BET bromodomain proteins could help treat glioma. The liposomal nanoparticles contain distearoylglycerophosphoethanolamine (DSPE) conjugated to polyethylene glycol (PEG) and...
BioCentury | May 23, 2018
Distillery Therapeutics

Cancer

INDICATION: Breast cancer; brain cancer; solid tumors Mouse studies suggest liposomal nanoparticles loaded with immunomodulatory agents could enhance the efficacy of CAR T therapies to treat solid cancers. The liposomal nanoparticles are coated with an...
BioCentury | Apr 4, 2018
Politics & Policy

CDER releases guidance on liposome products

...that are specific to the liposome's structure and integrity, as those properties reflect the ability of the liposome...
BioCentury | Dec 5, 2017
Distillery Techniques

Assays and screens

TECHNOLOGY: Cell-free assays; diagnostic assays An assay for detecting GPC1 mRNA in serum extracellular vesicles could help diagnose PDAC. The assay involves adding patient serum samples to a slide coated with cationic liposomes loaded with...
BioCentury | Oct 10, 2017
Distillery Therapeutics

Inflammation

INDICATION: Inflammation Cell culture and mouse studies suggest photosynthetic hydrogen-generating liposomes could help treat inflammation. The liposomes were loaded with three components: the red light photosensitizer chlorophyll a ; the proton donor ascorbic acid; and...
BioCentury | Jun 27, 2017
Distillery Techniques

Drug delivery

TECHNOLOGY: Nanoparticles Estrone-conjugated liposomes could be used to deliver therapies to ESR1 -positive tumors. The liposomes are composed of distearoylglycerophosphoethanolamine (DSPE) conjugated to polyethylene glycol (PEG) and the ESR1 ligand estrone and loaded with a...
BioCentury | May 4, 2017
Clinical News

FDA grants TLC178 rare pediatric disease designation

FDA granted rare pediatric disease designation to TLC178 from Taiwan Liposome Co. Ltd. (TPEx:4152) to treat rhabdomyosarcoma. The liposomal encapsulated formulation of vinorelbine has Orphan Drug designation from FDA to treat cutaneous T cell lymphoma...
Items per page:
1 - 10 of 335