BioCentury | Sep 19, 2020
Finance

Athira, Compass IPOs help quartet push biopharmas’ 2020 NASDAQ haul above $9B

...due in late 2022. The company believes that modulating the HGF-MET receptor system can recover synaptic...
BioCentury | Jul 15, 2020
Product Development

INmune therapy shows promise in Alzheimer’s, but cognitive test still to come

...inflammatory reactions.” Downstream, TNF prompts production of IL-1, IL-6, CCL2 and chemokines, which then cause synaptic...
...does not block transmembrane TNF, which protects neurons, improves immune response, promotes remyelination and improves synaptic...
BioCentury | Jun 5, 2020
Finance

With $85M series B, Athira seeks to recover neuronal health in Alzheimer’s patients

...Kawas told BioCentury that activating hepatocyte growth factor, also known as scatter factor, can recover synaptic...
BioCentury | May 23, 2020
Emerging Company Profile

Praxis: connecting the neurological dots

...PMD). While GABA biology is well-established, PRAX-114 preferentially modulates the neurotransmitter’s extrasynaptic receptors over the synaptic...
...will induce a more rapid and sustained antidepressant effect without the sedative side effects of synaptic-only...
BioCentury | Apr 1, 2020
Emerging Company Profile

Aspen plans to drive iPS cell therapy into Parkinson’s patients with $70M A round

...benefits of the autologous cells are that they may be able to better find their synaptic...
BioCentury | Mar 7, 2020
Product Development

If NoNO’s stroke trial strategy pays off, it could bring the first new therapy in a generation

...avoid the safety pitfalls of other neuroprotectant targets that have been pursued for stroke. The synaptic...
BioCentury | Feb 22, 2020
Product Development

Regenerative medicine for hearing loss makes quiet progress

...to induce proliferative differentiation, according to its website. Details of the mechanism are not disclosed. Synaptic...
...cells. “Many people lose hearing not because they lose hair cells but because they lose synaptic...
...need a product like OTO-413, because those new cells are going to need to establish synaptic...
BioCentury | Jan 29, 2020
Company News

Decibel narrows discovery focus to inner ear regeneration, taps Reid as CEO

...inner ear hair cells and auditory nerve fibers, and not in the cells themselves (see "Synaptic...
...its R&D, Decibel has been using single-cell sequencing to study hearing loss due to impaired synaptic...
BioCentury | Nov 15, 2019
Product Development

Minerva on the verge in neuropsychiatry with two compounds close to verdict

...limbic system, which is responsible for emotional processing. Functional studies have suggested sigma-2 receptors modulate synaptic...
BioCentury | Oct 23, 2019
Clinical News

Biogen’s aducanumab pleases investors, confounds doctors

...dose and time dependent, and there may be a lag between removal of amyloid and synaptic...
Items per page:
1 - 10 of 485
BioCentury | Sep 19, 2020
Finance

Athira, Compass IPOs help quartet push biopharmas’ 2020 NASDAQ haul above $9B

...due in late 2022. The company believes that modulating the HGF-MET receptor system can recover synaptic...
BioCentury | Jul 15, 2020
Product Development

INmune therapy shows promise in Alzheimer’s, but cognitive test still to come

...inflammatory reactions.” Downstream, TNF prompts production of IL-1, IL-6, CCL2 and chemokines, which then cause synaptic...
...does not block transmembrane TNF, which protects neurons, improves immune response, promotes remyelination and improves synaptic...
BioCentury | Jun 5, 2020
Finance

With $85M series B, Athira seeks to recover neuronal health in Alzheimer’s patients

...Kawas told BioCentury that activating hepatocyte growth factor, also known as scatter factor, can recover synaptic...
BioCentury | May 23, 2020
Emerging Company Profile

Praxis: connecting the neurological dots

...PMD). While GABA biology is well-established, PRAX-114 preferentially modulates the neurotransmitter’s extrasynaptic receptors over the synaptic...
...will induce a more rapid and sustained antidepressant effect without the sedative side effects of synaptic-only...
BioCentury | Apr 1, 2020
Emerging Company Profile

Aspen plans to drive iPS cell therapy into Parkinson’s patients with $70M A round

...benefits of the autologous cells are that they may be able to better find their synaptic...
BioCentury | Mar 7, 2020
Product Development

If NoNO’s stroke trial strategy pays off, it could bring the first new therapy in a generation

...avoid the safety pitfalls of other neuroprotectant targets that have been pursued for stroke. The synaptic...
BioCentury | Feb 22, 2020
Product Development

Regenerative medicine for hearing loss makes quiet progress

...to induce proliferative differentiation, according to its website. Details of the mechanism are not disclosed. Synaptic...
...cells. “Many people lose hearing not because they lose hair cells but because they lose synaptic...
...need a product like OTO-413, because those new cells are going to need to establish synaptic...
BioCentury | Jan 29, 2020
Company News

Decibel narrows discovery focus to inner ear regeneration, taps Reid as CEO

...inner ear hair cells and auditory nerve fibers, and not in the cells themselves (see "Synaptic...
...its R&D, Decibel has been using single-cell sequencing to study hearing loss due to impaired synaptic...
BioCentury | Nov 15, 2019
Product Development

Minerva on the verge in neuropsychiatry with two compounds close to verdict

...limbic system, which is responsible for emotional processing. Functional studies have suggested sigma-2 receptors modulate synaptic...
BioCentury | Oct 23, 2019
Clinical News

Biogen’s aducanumab pleases investors, confounds doctors

...dose and time dependent, and there may be a lag between removal of amyloid and synaptic...
Items per page:
1 - 10 of 485