00:04 , Jul 19, 2019 |  BC Extra  |  Financial News

Genmab’s plans after $500M NASDAQ debut

European bellwether Genmab plans to use a large chunk of the $505.9 million it raised through its listing on NASDAQ Thursday to fuel clinical development and commercialization of antibody-drug conjugate tisotumab vedotin (HuMax-TF-ADC). Two other...
22:59 , Jul 18, 2019 |  BC Innovations  |  Emerging Company Profile

Neoleukin emerges with a de novo approach to improving biologics

With a platform to design proteins from scratch, Neoleukin is making a new class of biologics that resemble their endogenous protein counterparts in structure, but not in sequence. The strategy gives the company a clean...
00:02 , Jul 17, 2019 |  BC Extra  |  Company News

July 16 Company Quick Takes: Mazumdar-Shaw, Mukherjee to bring CAR Ts to India; plus Cipla, Celgene, Novartis, Seattle Genetics

Immuneel founded to bring CAR T therapies to India  Kiran Mazumdar-Shaw and Siddhartha Mukherjee founded Immuneel Therapeutics Ltd. (Bangalore, India) with the goal of providing affordable CAR T cell therapies to Indian patients. Mazumdar-Shaw is...
01:58 , Jun 29, 2019 |  BioCentury  |  Finance

Biotech backs down in 2Q19

In a reversal from 1Q19, biotech stocks across all market cap tiers fell in the second quarter, leading to a total loss of $22.3 billion. However, the year-to-date change in market cap remains well in...
00:47 , Jun 29, 2019 |  BioCentury  |  Finance

All eyes on new modality launches, cancer and rare disease data in 3Q19

While the typical summer lull means fewer catalysts in the third quarter, investors will be keeping a close eye on launches of new modality drugs. Of special interest to multiple buysiders is the launch of...
01:37 , Jun 28, 2019 |  BC Innovations  |  Product Development

How Array stayed alive long enough to grow up

Array’s 21-year journey as an independent platform company, culminating in an $11.4 billion buyout, required shifting focus from research to development and back again. The acquisition sends a message that developing focused expertise and sticking...
03:07 , Jun 7, 2019 |  BC Innovations  |  Targets & Mechanisms

Following PARP, ATR axis next in line to expand synthetic lethal drug class

Promising ASCO readouts suggest targets in the ATR pathway are lining up behind PARP as the next drivers of “synthetic lethal” cancer killing. Biomarker and combination strategies presented at the American Society of Clinical Oncology...
14:09 , Jun 3, 2019 |  BC Extra  |  Clinical News

Astellas, Seattle Genetics ADC could provide new option for checkpoint non-responders in bladder cancer

Data presented at ASCO on Monday for Astellas and Seattle Genetics' enfortumab vedotin showed that metastatic bladder cancer patients who don't respond or relapse after PD-1/PD-L1 therapy could soon have a new treatment option. In...
02:43 , Jun 1, 2019 |  BioCentury  |  Product Development

ASCO 2019 abstracts show solid tumor race heating up among bispecifics and CAR Ts

While strong progress in CAR T therapies will again feature at this year’s ASCO meeting, bispecific antibodies are having a moment -- making more inroads into solid tumors than CAR Ts and branching out via...
19:06 , May 22, 2019 |  BC Extra  |  Company News

Management tracks: Gottlieb re-joining NEA; plus Seattle Genetics, Celsius and more

Former FDA Commissioner Scott Gottlieb is joining New Enterprise Associates as a special partner. Gottlieb was a venture partner at the firm from 2007 to 2017. In his new role, Gottlieb will have a “deeper...