22:50 , Nov 13, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: B cell lymphoma Cell and mouse studies suggest promoting PMAIP1 expression or inhibiting MCL1 could enhance the efficacy of BCL-2 inhibitors to treat diffuse large B cell lymphoma (DLBCL). In a DLBCL cell line,...
23:49 , Nov 9, 2018 |  BC Extra  |  Company News

Management tracks: Denali, Convert

Neurology company Denali Therapeutics Inc. (NASDAQ:DNLI) appointed Jennifer Cook to its board. She is CEO of Grail Inc. (Menlo Park, Calif.) and previously was global head of clinical operations of Roche (SIX:ROG; OTCQX:RHHBY). Convert Pharmaceuticals...
20:15 , Nov 9, 2018 |  BC Week In Review  |  Clinical News

FDA extends review of Samsung Bioepis' trastuzumab biosimilar

A Samsung Bioepis Co. Ltd. spokesperson told BioCentury that FDA extended by three months its review of a BLA for SB3, a biosimilar of cancer drug Herceptin trastuzumab from Roche (SIX:ROG; OTCQX:RHHBY) and its Genentech...
18:45 , Nov 9, 2018 |  BC Week In Review  |  WIR Deals New Deals

AbbVie gains Parkinson’s pipeline from BioArctic

AbbVie Inc. (NYSE:ABBV) gained exclusive, worldwide rights to a pipeline of antibodies targeting α-synuclein (SNCA) to treat Parkinson’s disease for $50 million through an option exercise with BioArctic AB (SSE:BIOA B). The deal is valued...
18:31 , Nov 9, 2018 |  BC Week In Review  |  Clinical News

Sandoz gives up on Rituxan biosimilar in U.S.

With two competing biosimilars under FDA review, Sandoz will no longer seek U.S. approval of GP2013, its biosimilar of cancer and autoimmune drug Rituxan/MabThera rituximab from Roche (SIX:ROG; OTCQX:RHHBY). The unit of Novartis AG (NYSE:NVS;...
18:10 , Nov 9, 2018 |  BC Week In Review  |  Company News

Genentech seeks to block JHL from using trade secrets

Genentech Inc. is asking a federal court to block JHL Biotech Inc. (Zhubei, Taiwan) from making and selling products the company claims benefited from its proprietary information, following the indictment of three former Genentech employees...
01:14 , Nov 9, 2018 |  BC Extra  |  Company News

FDA extends review of Samsung Bioepis' trastuzumab biosimilar

A Samsung Bioepis Co. Ltd. spokesperson told BioCentury that FDA extended by three months its review of a BLA for SB3, a biosimilar of cancer drug Herceptin trastuzumab from Roche (SIX:ROG; OTCQX:RHHBY) and its Genentech...
00:40 , Nov 8, 2018 |  BC Extra  |  Company News

Genentech seeks to block JHL from using trade secrets

Genentech Inc. is asking a federal court to block JHL Biotech Inc. (Zhubei, Taiwan) from making and selling products the company claims benefited from its proprietary information, following the indictment of three former Genentech employees...
23:24 , Nov 7, 2018 |  BC Extra  |  Company News

Management tracks: Myovant, Alkahest

Women’s health and endocrine disease company Myovant Sciences Ltd. (NYSE:MYOV) named Kim Sablich chief commercial officer and Jeff Nornhold SVP of pharmaceutical operations and development. Sablich was VP of primary care marketing in the U.S....
20:48 , Nov 6, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Respiratory syncytial virus (RSV) Cell culture, mouse and rat studies identified an RSV F protein inhibitor that could help treat RSV infection. Optimization and testing in HeLa cell-based assays of a previously reported quinoline-based...