17:25 , Sep 14, 2018 |  BC Week In Review  |  Financial News

OncoResponse to move into clinic with $40M series B

OncoResponse Inc. (Houston, Texas) raised $40 million in a series B round led by RiverVest Venture Partners. Fellow new investors Qatar Investment Authority and Redmile Group participated, as did existing investors Alexandria Venture Investments, Arch...
22:22 , Sep 11, 2018 |  BC Extra  |  Financial News

OncoResponse to move into clinic with $40M series B

OncoResponse Inc. (Houston, Texas) raised $40 million in a series B round led by RiverVest Venture Partners. Fellow new investors Qatar Investment Authority and Redmile Group participated, as did existing investors Alexandria Venture Investments, Arch...
17:52 , May 3, 2018 |  BC Innovations  |  Translation in Brief

Tuning thresholds

Synthetic biologists at Rice University have figured out how to tune naturally occurring bacterial biosensors to detect clinically relevant levels of target molecules. The group intends to use the approach to engineer gut microbes that...
19:09 , Aug 22, 2017 |  BC Innovations  |  Distillery Techniques

Drug delivery

TECHNOLOGY: Nanoparticles Magnetic nanoparticles that enhance vascular permeability in response to magnetic fields could help deliver therapeutic agents across blood vessels. The nanoparticles consist of magnetic iron oxide nanocrystals coated with polyethylene glycol (PEG). In...
19:09 , Feb 22, 2017 |  BC Innovations  |  Distillery Techniques

Chemistry

TECHNOLOGY: Synthetic chemistry A method of using bacterial enzymes to add prenyl groups to aryl-containing scaffolds could enable the discovery of novel bioactive molecules. The single-step chemical reaction involved utilizing C-prenyltransferases derived from a Streptomyces...
00:45 , Dec 22, 2016 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Ovarian cancer Patient sample, cell culture and mouse studies suggest inhibiting USP13 could help treat ovarian cancer. In patient samples, levels of USP13 were higher in tumors than in adjacent normal ovarian tissue, and...
20:46 , Dec 15, 2016 |  BC Innovations  |  Targets & Mechanisms

Keeping the Gas off AXL

With its development of an AXL decoy able to trap and sequester the native receptor’s ligand with femtomolar affinity, Aravive Biologics Inc. believes it has a biologic that can bypass the potency and selectivity issues...
07:00 , Oct 27, 2016 |  BC Innovations  |  Translation in Brief

Random math

Compressed sensing is a mathematical theory for extracting sparse signals from a sea of noise that has spawned inventions ranging from the single-pixel camera to facial recognition software. Now, a team from Rice University has...
07:00 , Aug 8, 2016 |  BioCentury  |  Emerging Company Profile

Interrogating immunity

OncoResponse Inc. is repurposing Theraclone Sciences Inc .'s I-STAR discovery platform to identify antibodies produced by exceptional responders to cancer immunotherapy. By tapping patients' natural immune responses, OncoResponse hopes to find novel immune targets and...
07:00 , Apr 28, 2016 |  BC Innovations  |  Finance

Bridging translation

An increasing number of academic institutions are filling the translational gap between what typical academic projects produce and what companies or VC firms want to see in order to commercialize a discovery. These organizations, or...