BioCentury | Oct 18, 2018
Preclinical News

Flurry of news highlights latest in switch-controlled gene therapy

...the Janssen Pharmaceuticals Inc. unit of Johnson & Johnson (NYSE:JNJ) announced a deal to develop ribozyme-based...
BioCentury | Apr 25, 2018
Translation in Brief

Mo’ TERT, mo’ liver cells

...led by Steven Artandi hypothesized that telomerase reverse transcriptase (TERT), the protein subunit of the ribozyme...
BioCentury | Jun 29, 2017
Preclinical News

Paper describes inducible CRISPR

...sgRNA, the group also incorporated an aptazyme, which contains a ligand binding aptamer and a ribozyme...
BioCentury | Jun 29, 2017
Preclinical News

Paper describes inducible CRISPR

...sgRNA, the group also incorporated an aptazyme, which contains a ligand binding aptamer and a ribozyme...
BioCentury | Feb 20, 2014
Distillery Techniques

Technology: Drug platforms

Approach Summary Licensing status Publication and contact information Drug platforms Viral insertion of inducible aptazymes to improve the safety of oncolytic viral therapy In vitro studies suggest inducible aptazymes that regulate viral gene expression could...
BioCentury | Apr 15, 2013
Company News

IntelliGene Ltd., Ribozyme deal

...IntelliGene, a diagnostics company, has a subsidiary in Sudbury, Mass. IntelliGene Ltd. , Jerusalem, Israel Ribozyme Pharmaceuticals Inc....
BioCentury | Apr 15, 2013
Clinical News

Ribozyme regulatory update

...RZYM received U.S. Patent No. 5,612,215 covering ribozyme molecules that enzymatically cleave stromelysin, a matrix metalloproteinase...
...The patent covers the ribozyme technology as well as its application to specific therapeutic targets. Ribozyme Pharmaceuticals Inc....
BioCentury | Jul 15, 2010
Distillery Therapeutics

Indication: Infectious disease

...HIV/AIDS. Benitec Ltd. has a lentiviral vector encoding three forms of anti-HIV RNA including a ribozyme...
BioCentury | Jul 15, 2010
Cover Story

Zinc-ing differently about HIV

...CXCR4 and viral proteins involved in replication. Benitec's lentivirus-based therapy for HSCs combines a CCR5-disrupting ribozyme...
BioCentury | Sep 24, 2009
Distillery Techniques

Technology: Drug platforms

...could provide a platform for developing inducible siRNA therapeutics. Aptazymes are aptamers conjugated to a ribozyme...
Items per page:
1 - 10 of 240
BioCentury | Oct 18, 2018
Preclinical News

Flurry of news highlights latest in switch-controlled gene therapy

...the Janssen Pharmaceuticals Inc. unit of Johnson & Johnson (NYSE:JNJ) announced a deal to develop ribozyme-based...
BioCentury | Apr 25, 2018
Translation in Brief

Mo’ TERT, mo’ liver cells

...led by Steven Artandi hypothesized that telomerase reverse transcriptase (TERT), the protein subunit of the ribozyme...
BioCentury | Jun 29, 2017
Preclinical News

Paper describes inducible CRISPR

...sgRNA, the group also incorporated an aptazyme, which contains a ligand binding aptamer and a ribozyme...
BioCentury | Jun 29, 2017
Preclinical News

Paper describes inducible CRISPR

...sgRNA, the group also incorporated an aptazyme, which contains a ligand binding aptamer and a ribozyme...
BioCentury | Feb 20, 2014
Distillery Techniques

Technology: Drug platforms

Approach Summary Licensing status Publication and contact information Drug platforms Viral insertion of inducible aptazymes to improve the safety of oncolytic viral therapy In vitro studies suggest inducible aptazymes that regulate viral gene expression could...
BioCentury | Apr 15, 2013
Company News

IntelliGene Ltd., Ribozyme deal

...IntelliGene, a diagnostics company, has a subsidiary in Sudbury, Mass. IntelliGene Ltd. , Jerusalem, Israel Ribozyme Pharmaceuticals Inc....
BioCentury | Apr 15, 2013
Clinical News

Ribozyme regulatory update

...RZYM received U.S. Patent No. 5,612,215 covering ribozyme molecules that enzymatically cleave stromelysin, a matrix metalloproteinase...
...The patent covers the ribozyme technology as well as its application to specific therapeutic targets. Ribozyme Pharmaceuticals Inc....
BioCentury | Jul 15, 2010
Distillery Therapeutics

Indication: Infectious disease

...HIV/AIDS. Benitec Ltd. has a lentiviral vector encoding three forms of anti-HIV RNA including a ribozyme...
BioCentury | Jul 15, 2010
Cover Story

Zinc-ing differently about HIV

...CXCR4 and viral proteins involved in replication. Benitec's lentivirus-based therapy for HSCs combines a CCR5-disrupting ribozyme...
BioCentury | Sep 24, 2009
Distillery Techniques

Technology: Drug platforms

...could provide a platform for developing inducible siRNA therapeutics. Aptazymes are aptamers conjugated to a ribozyme...
Items per page:
1 - 10 of 240