Pelago and AstraZeneca partnered to develop assay formats and applications of the Cellular Thermal Shift Assay (CETSA) across the range of AZ’s therapeutic areas. Under the two-year, non-exclusive deal, the companies will collaborate on undisclosed...

Approach Summary Licensing status Publication and contact information Assays & screens Measuring target engagement in samples An assay to detect ligand binding in cells could be used to assess target engagement during preclinical and clinical...

Determining whether a compound binds its intended target is a fundamental question in drug discovery, but assays for measuring target engagement in vivo can be indirect and inconclusive. To remedy the situation, a Swedish group...