INDICATION: Neurology Mouse models suggest clearing senescent cells could help treat tau-mediated neurodegenerative diseases. In a mouse model of tauopathy expressing mutant human tau in neurons, systemic expression of a fusion human transgene based on...

A study in Cell has uncovered a brain regulatory network involving a circular RNA, a long non-coding RNA and two microRNAs, and could provide some much needed insights in a field where finding links to...

In drug discovery for neurodegenerative diseases, the emphasis is on finding better models of neuronal systems that recapitulate synapses, neuroinflammation and the pathological accumulation of toxic aggregates. Yumanity Therapeutics LLC and a handful of academic...

Although sanofi-aventis Group has not hidden the fact it has moved three antidepressant and anxiolytic molecules into late-stage development, it has revealed few details. Now, the company is beginning to lift the veil, describing the...

Layton (Atherton, Calif.) granted La Jolla-based Strategene exclusive marketing rights to Layton's hNT human neuronal cells for research use in the U.S., Canada and Europe. Layton said the hNT neurons will allow researchers to study...