Liquid biopsy company Thrive Earlier Detection Corp. hired Sam Asgarian as CMO, Frank Diehl as EVP of product solutions and Dina Ciarimboli as chief legal officer. Before joining Thrive, Asgarian was VP of the transformation health product organization at...

Meditope Biosciences Inc. , Pasadena, Calif. Business: Antibodies, Cancer Transitioned: Bob McKenzie to EVP of business development, while remaining a director WIR Staff cancer...

Meditope Biosciences Inc. 's meditope-enabled linker technology could improve upon first-generation antibody-drug conjugates by producing ADCs that are more stable and homogeneous. First-generation ADC technologies typically link cytotoxic agents to naturally occurring amino acids on...

Approach Summary Licensing status Publication and contact information Drug platforms Functionalizing mAbs with a noncovalent peptide-binding site A peptide-binding site found on Erbitux cetuximab could be used to functionalize mAbs without disrupting their native antigen-binding...

Linker technologies for generating antibody-drug conjugates typically require a labor-intensive process of reengineering the antibody for every application. Researchers at the Beckman Research Institute at City of Hope have published proof-of-concept data on a platform...

After about 25 years of development, antibody-drug conjugates have gained acceptance as a validated approach to the targeted killing of cells, with two drugs approved in the past two years. While Seattle Genetics Inc. and...

Meditope Biosciences Inc. , Pasadena, Calif. Business: Antibodies Hired: Elisabeth Gardiner as CSO, formerly director of physiology at aTyr Pharma Inc. WIR Staff...

Meditope Biosciences Inc. , Pasadena, Calif. Business: Antibodies, Cancer Date completed: 7/26/13 Type: Venture financing Raised: $3.6 million Investors: Angel investors WIR Staff cancer...

Meditope Biosciences Inc. (Pasadena, Calif.) raised $3.6 million in a series A round from angel investors. The company is developing a technology to link antibodies to payloads without the need for chemical conjugation. Meditope also...