This week in therapeutics Indication Target/marker/pathway Summary Licensing status Publication and contact information Infectious disease Crohn's disease Bacterial fimbrial adhesin (fimH) Cell culture and ex vivo studies suggest thiazolylaminomannosides could help treat Crohn's disease. Adherent-invasive...

The intestinal flora of patients with Crohn's disease is frequently populated by adherent-invasive Escherichia coli , which cause intestinal inflammation. Although this inflammatory response is typically treated with tumor necrosis factor -lowering therapies, University of Nantes...