07:00 , Oct 5, 2015 |  BC Week In Review  |  Financial News

Encycle Therapeutics completes venture financing

Encycle Therapeutics Inc. , Toronto, Ontario   Business: Chemistry, Autoimmune, Cancer   Date completed: 2015-09-30   Type: Venture financing   Raised: C$2.9 million ($2.1 million)   Investors: Takeda Ventures Inc.; Accel-Rx Health Sciences Accelerator; BDC...
00:50 , May 2, 2015 |  BC Extra  |  Company News

Merck, PeptiDream to develop macrocycles

Merck & Co. Inc. (NYSE:MRK) and PeptiDream Inc. (Tokyo:4587) have partnered to use the biotech's Peptide Discovery Platform System (PDPS) to generate macrocycles against multiple undisclosed targets selected by Merck. Merck will have the right...
08:00 , Dec 18, 2014 |  BC Innovations  |  Translation in Brief

YABAO GOES BOLD

Yabao goes bold China-based Yabao Pharmaceutical Group Co. Ltd. and MRC Technology are jointly going where Western pharmas and academics fear to tread with a preclinical partnership to develop compounds against an undisclosed kinase target...
08:00 , Dec 4, 2014 |  BC Innovations  |  Strategy

Merck Encycles through Canada

The first disclosed grant under Merck & Co. Inc. 's Canadian translational initiative will bolster the ability of macrocycle-based Encycle Therapeutics Inc. to conduct lead optimization of its integrin α4b7 inhibitors for inflammatory bowel disease....
07:00 , Aug 4, 2014 |  BioCentury  |  Emerging Company Profile

Encycle: Oral macrocycles

Macrocycle therapies can block protein-protein interactions that are undruggable with small molecules; however, oral availability and cell penetration remain key challenges. Encycle Therapeutics Inc. 's chemistry platform generates drug-like macrocycles against validated targets to treat...
07:00 , Sep 17, 2012 |  BioCentury  |  Product Development

Excited about cycling

New synthesis and screening technologies and the allure of access to previously undruggable targets are driving an explosion of new company formation and deal-making around macrocycles and constrained peptides. While it remains to be seen...
07:00 , Jul 9, 2012 |  BC Week In Review  |  Company News

MaRS Innovation, Quebec Consortium for Drug Discovery (CQDM) chemistry news

MaRS Innovation spun out Encycle Therapeutics Inc. to develop a chemistry technology that cyclizes linear peptides for use in drug discovery research. MaRS said that the technology will increase efficiency of the early-stage discovery process...