Indication Target/marker/pathway Summary Licensing status Publication and contact information Renal disease Glomerulonephritis Chemokine CX3C motif receptor 1 (CX3CR1) Mouse studies suggest inhibiting CX3CR1 could help treat glomerulonephritis. In a mouse model of crescentic glomerulonephritis, Cx3cr1...

Researchers in the EU and the U.S. have found what could be the mechanistic underpinnings of the increased risk for age-related macular degeneration in individuals carrying a common polymorphism in the gene for complement factor...

Indication Target/marker/pathway Summary Licensing status Publication and contact information Renal disease Glomerulonephritis Macrophage mannose receptor (MR) Mouse studies suggest that inhibiting MR could help treat crescentic glomerulonephritis, which can lead to end-stage kidney disease. In...

More than meets the eye New imaging technology can provide more and better information. The angiogram on the left appears normal. However, intravascular ultrasound reveals a varying extent of atherosclerosis in two sites in the...