21:59 , Jul 11, 2019 |  BC Innovations  |  Targets & Mechanisms

The tumor stroma rises as the newest source of immuno-oncology targets

With a spate of therapies entering the clinic, the next frontier in the fight against resistance to checkpoint inhibitors will be the stroma. The lead target marks a resurgence of interest in TGFβ, and behind...
01:39 , Jun 29, 2019 |  BioCentury  |  Finance

Specialists and strong fundamentals must carry the sector in 3Q19

Heading into the third quarter, specialist biotech investors are in the driver’s seat, and their stances on whether to trim or spend in the down market are split. After recovering at the start of the...
21:02 , Jun 27, 2019 |  BC Extra  |  Financial News

Syncona reaps tenfold return from Blue Earth exit

Returns from the sale of Blue Earth Diagnostics for $450 million will allow majority shareholder Syncona to reinvest in its maturing portfolio companies as they scale, and will also drive new company launches, the firm's...
20:45 , Jun 6, 2019 |  BC Extra  |  Financial News

How Third Rock will deploy $770M in its biggest fund yet

Staff changes and recent trends in private capital dynamics aren’t likely to sway Third Rock Ventures’ strategy as it invests its new $770 million Fund V, the firm’s largest-ever vehicle. The firm will, however, have...
20:49 , May 24, 2019 |  BioCentury  |  Finance

How Europe’s hotspots of innovation could fuel its rise as a global player in new modalities

It is clear that Europe has hotspots of innovation that are discovering and developing the next wave of new therapeutic modalities. Nearly every category of new modality has a European champion, with clusters forming around...
01:42 , May 4, 2019 |  BioCentury  |  Product Development

How the amyloid hypothesis holds its grip

By now, two things are clear about the amyloid hypothesis of Alzheimer’s disease: one is that the amyloid peptide is somehow involved; the other is that it’s a terrible target. β amyloid has had an...
20:12 , Apr 23, 2019 |  BC Extra  |  Politics & Policy

Biopharma battling drug price regulations in Massachusetts

The Massachusetts House of Representatives is set to vote this week on a bill that would regulate the prices of the highest-cost drugs purchased by the state’s MassHealth Medicaid program. Massachusetts biopharma companies are fighting...
18:10 , Apr 23, 2019 |  BioCentury  |  Finance

Accelerating innovations in Cambridge

As the Cambridge, U.K., life sciences start-up environment continues to flourish, Cambridge Innovation Capital’s Michael Anstey believes the city lacked a crucial element to foster start-ups’ growth: a “true U.S.-style accelerator” to provide capital, mentorship...
11:00 , Apr 18, 2019 |  BioCentury  |  Finance

Arranging Arrakis' syndicate

As it raised a $75 million series B round that will help its early research coalesce into a preclinical pipeline, Arrakis sought an investor syndicate that would build its expertise as it seeks to become...
00:16 , Apr 6, 2019 |  BioCentury  |  Finance

Room to rally in 2Q

Strong small and mid-cap performance coupled with robust M&A has brought the sector back from 4Q18 correction territory, and chances are good for the momentum to continue given the ample capital ready to be recycled...