22:17 , Jun 20, 2019 |  BC Extra  |  Company News

Gene therapy, vaccines in focus as Sanofi maps out priorities

As Sanofi continues to pull back from diabetes and cardiovascular diseases, the French pharma is turning toward gene therapy and intensifying its focus on vaccines and cancer ahead of this fall’s CEO change. The shift...
23:33 , Jun 17, 2019 |  BC Extra  |  Company News

Sanofi shies away from neuro gene therapy programs

Changes to two partnerships this year suggest Sanofi is paring down the disease areas in which it wants to deploy gene therapy. The latest came on Monday, when Voyager Therapeutics Inc. (NASDAQ:VYGR) said it and...
17:48 , May 28, 2019 |  BC Innovations  |  Distillery Techniques

Raising lentiviral surface levels of CD47 to improve therapeutic index

TECHNIQUES CATEGORY: Drug delivery; drug platforms TECHNOLOGY: Viral vectors; gene therapy A method for increasing the surface density of CD47 on lentiviral vectors could enhance the safety and duration of Factor IX-based hemophilia B gene...
23:01 , May 22, 2019 |  BC Extra  |  Preclinical News

SR-Tiget-led team boosts ‘don’t eat me’ signals on viral vectors to improve efficacy

Boosting surface levels of a "don't eat me" signal on lentiviral vectors could enable administration of lower gene therapy doses and prevent immune responses by shielding the vectors from phagocytosis. HIV-derived lentiviral gene therapy vectors...
14:31 , Apr 26, 2019 |  BC Extra  |  Financial News

Schizophrenia therapy developer Karuna among four biotechs to file for IPOs

Weeks after completing its $80 million series B round, antipsychotic therapy developer Karuna said it has filed confidential documentation with the SEC for a planned IPO. The company was one of four to unveil plans...
23:09 , Mar 29, 2019 |  BC Extra  |  Company News

Management tracks: Insmed, AACR, BlueRock

Pulmonary disease company Insmed said Paolo Tombesi will step down as CFO and remain a consultant, effective June 2. Insmed Inc. (NASDAQ:INSM) will begin to search for a successor. It also promoted John Goll to...
22:14 , Feb 21, 2019 |  BC Extra  |  Company News

Management tracks: Mirati, Verastem, RedHill

Oncology company Mirati Therapeutics Inc. (NASDAQ:MRTX) named Faheem Hasnain as chairman. He succeeds Rodney Lappe, who is retiring but will remain a consulting adviser. Hasnain is executive chairman of Gossamer Bio Inc. (NASDAQ:GOSS), which raised...
22:10 , Jan 25, 2019 |  BC Extra  |  Company News

Management Tracks: Zealand, BeiGene

Zealand Pharma A/S (CSE:ZEAL; NASDAQ:ZEAL) said EVP and Chief Medical and Development Officer Adam Steensberg will become interim CEO on March 1. He will succeed Britt Meelby Jensen, who is leaving the company on Feb....
19:32 , Dec 14, 2018 |  BC Week In Review  |  Company News

Biogen returns gene therapies to AGTC on lack of clinical activity

Applied Genetic Technologies Corp. (NASDAQ:AGTC) said late Dec. 12 that Biogen Inc. (NASDAQ:BIIB) terminated the companies’ gene therapy collaboration, leaving behind a partnership originally established to help Biogen build its gene therapy expertise. AGTC was...
23:34 , Dec 13, 2018 |  BC Extra  |  Company News

Biogen returns gene therapies to AGTC on lack of clinical activity

Applied Genetic Technologies Corp. (NASDAQ:AGTC) said late Wednesday that Biogen Inc. (NASDAQ:BIIB) terminated the companies’ gene therapy collaboration, leaving behind a partnership originally established to help Biogen build its gene therapy expertise. AGTC was down...