00:06 , Jan 23, 2019 |  BC Innovations  |  Distillery Techniques

Disease models

TECHNOLOGY: 3-D models A 3-D human tissue model that mimics beating adult myocardium could help assess the effects of heart disease therapies on myocardial contractility. Generation and use of the biomimetic model involves five steps:...
04:55 , Jan 19, 2018 |  BC Week In Review  |  Clinical News

CellMax reports colorectal cancer diagnostic data

CellMax Life Inc. (Sunnyvale, Calif.) reported that its CellMax-CRC colorectal cancer screening test detected colorectal cancer with 84% sensitivity and 97.3% specificity. The single-site, Taiwanese trial enrolled 620 adults who were undergoing a routine colonoscopy...
23:24 , Jan 17, 2018 |  BC Extra  |  Clinical News

Exact Sciences falls on CellMax cancer diagnostic data

Exact Sciences Corp. (NASDAQ:EXAS) was off $5.27 (10%) to $47.68 on Wednesday after CellMax Life Inc. (Sunnyvale, Calif.) reported that its CellMax-CRC colorectal cancer screening test detected colorectal cancer with 84% sensitivity and 97.3% specificity....
21:31 , Dec 19, 2017 |  BC Innovations  |  Distillery Therapeutics

Gastrointestinal

INDICATION: Short bowel syndrome A bioengineered intestinal transplant could help treat short bowel syndrome. The transplant consists of a decellularized segment of rat proximal jejunum seeded with human endothelial cells and human induced pluripotent stem...
21:31 , Dec 16, 2016 |  BC Week In Review  |  Company News

Kubota, EyeMedics deal

EyeMedics and Kubota's Acucela Inc. subsidiary partnered to develop lipoxin biomimetic small molecules to treat, prevent and diagnose ophthalmic diseases, with an initial focus on diabetic macular edema (DME). EyeMedics will be responsible for preclinical...
08:00 , Feb 18, 2016 |  BC Innovations  |  Translation in Brief

Poring over DNA

Researchers at University College London (UCL) have built "lockable" DNA nanopores that control the release of molecular cargo from vesicles using oligonucleotide "keys". The team thinks the straightforward design principles and low cost of DNA...
08:00 , Jan 5, 2015 |  BioCentury  |  Emerging Company Profile

Mimicking proteoglycans

Symic Biomedical Inc. is developing a library of synthetic mimics that function like natural proteoglycans but are easier to manufacture and aren't susceptible to enzymatic degradation, opening up previously untapped therapeutic space. Proteoglycans, which are...
07:00 , Sep 18, 2014 |  BC Innovations  |  Tools & Techniques

Bad blood

Whereas pharmacological approaches to treating sepsis have languished in the clinic, a mechanical approach has been designed by a Massachusetts team that cleanses pathogens and endotoxins from blood. 1 The microfluidic device could be a...
08:00 , Feb 10, 2014 |  BC Week In Review  |  Company News

Applied Genetic Tech management update

Applied Genetic Technologies Corp. , Alachua, Fla.   Business: Gene/Cell therapy   Hired: Larry Bullock as CFO, formerly corporate secretary and CFO of BioMimetic Therapeutics Inc. , which Wright Medical Group Inc. acquired  ...
07:00 , Oct 10, 2013 |  BC Innovations  |  Distillery Techniques

Technology: Drug platforms

Approach Summary Licensing status Publication and contact information Drug platforms Integrated approach to accelerate biomimetic material engineering An integrated platform that combines RNA-seq with standard proteomics and materials science approaches could accelerate the development of...