23:08 , Mar 20, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Neuropathy Mouse studies suggest the small molecule FLT3 inhibitor BDT001 could help treat peripheral neuropathy. In one mouse model of nerve injury-induced and two mouse models of chemically-induced peripheral neuropathy, FLT3 knockout decreased mechanical...
19:51 , Mar 14, 2018 |  BC Extra  |  Preclinical News

FLT3 inhibitor reduces peripheral neuropathic pain

A study published in Nature Communications suggests that inhibiting FMS-like tyrosine kinase 3 (FLT3; CD135) with a small molecule inhibitor could help treat peripheral nerve pain. Current therapies to treat peripheral nerve pain, including off-label...