19:30 , Aug 8, 2019 |  BC Innovations  |  Distillery Techniques

Model to predict CRISPR repair outcomes in T cells

TECHNIQUES CATEGORY: Other TECHNOLOGY: Computational models Researchers from the Chan Zuckerberg Biohub, including co-founders of Spotlight Therapeutics Inc. and Arsenal BioSciences Inc., developed a machine-learning model dubbed SPROUT to predict the length, probability and sequence...
22:27 , Jul 31, 2019 |  BC Extra  |  Preclinical News

July 31 Preclinical Quick Takes: Sangamo reveals new gene editors; plus a CRISPR prediction model and vaccine boosters for ischemia

Sangamo unveils next-gen ZFN editors  In a Nature Biotechnology study , Sangamo Therapeutics Inc. (NASDAQ:SGMO) reported a next generation zinc finger nuclease (ZFN) gene editing technology with amino acid substitutions in the enzyme’s catalytic domain...