03:20 , Feb 16, 2019 |  BioCentury  |  Product Development

ADCs’ inflection point

Industry is writing a new rule book for antibody-drug conjugates that could take the modality beyond the one-size-fits-all approach that has limited its success. By 2Q20, late-stage data from at least four ADCs testing new...
22:15 , Aug 2, 2018 |  BC Innovations  |  Tools & Techniques

Model firsts

By combining disparate data into coherent mechanistic models, quantitative systems pharmacology is becoming a key tool for picking the right dose for first-in-human trials and other early make-or-break decisions. Advocates see it as part of...
19:53 , Apr 27, 2018 |  BC Week In Review  |  Company News

Sanofi, Applied BioMath partner to develop mAb combos

Mechanistic modeling company Applied BioMath LLC (Lincoln, Mass.) will assess the risk and feasibility of multispecific combinations and compare them to fixed dose combinations for multiple undisclosed targets in order to help Sanofi (Euronext:SAN; NYSE:SNY)...