08:00 , Mar 11, 2010 |  BC Innovations  |  Targets & Mechanisms

Blocking brain tumor rebound

California researchers have uncovered a key role for the interaction of CXCR4 and SDF-1 in the recurrence of glioblastoma multiforme (GBM), handing Genzyme Corp. a potential new indication for its CXCR4 inhibitor, Mozobil plerixafor. 1...
07:00 , Sep 10, 2009 |  BC Innovations  |  Distillery Techniques

Technology: Imaging

Approach Summary Licensing status Publication and contact information Imaging Replication-competent adenovirus expressing green fluorescent protein to detect circulating tumor cells OBP-401, an adenovirus-based imaging agent, could help quantify levels of circulating tumor cells in peripheral...
07:00 , Sep 3, 2009 |  BC Innovations  |  Distillery Techniques

Technology: Imaging

Approach Summary Licensing status Publication and contact information Imaging Telomerase-dependent, replication-competent adenovirus expressing green fluorescent protein to guide tumor resection OBP-401, a telomerase-dependent, adenovirus-based imaging agent, could help guide the surgical resection of tumor tissue....
07:00 , Aug 24, 2009 |  BC Week In Review  |  Clinical News

AntiCancer, Oncolys Biopharma preclinical data

In mouse models of disseminated cancer, OBP-401 labeled all cancer present and fluoresced under a simple lighting and filter apparatus. OBP-401 is an adenovirus encoding the human telomerase reverse transcriptase (hTERT) promoter and green fluorescent...
08:00 , Jan 2, 2006 |  BC Week In Review  |  Clinical News

AntiCancer preclinical data

In mice with severed legs, injection of hair follicle stem cells rejoined the nerves and helped regain function, enabling the mice to walk normally again. AntiCancer Inc. , San Diego, Calif.   Product: Hair follicle...
07:00 , Oct 24, 2005 |  BC Week In Review  |  Company News

AntiCancer, U.S. BioDefense Inc. deal

The companies partnered to develop therapeutics for neural diseases using human neural crest stem cells. Further terms were not disclosed. AntiCancer Inc. , San Diego, Calif.   U.S. BioDefense Inc. (UBDE), City of Industry, Calif....
07:00 , Jul 21, 2003 |  BC Week In Review  |  Clinical News

A/C Enzymatic Homocysteine Assay regulatory update

The FDA granted marketing clearance to AntiCancer's A/C Diagnostics unit for its test for homocysteine, a risk factor in cardiovascular and other diseases. AntiCancer Inc. , San Diego, Calif.   Product: A/C Enzymatic Homocysteine Assay...
07:00 , Jul 7, 2003 |  BC Week In Review  |  Company News

AntiCancer, Roswell Park Cancer Institute deal

AntiCancer and the institute will combine MRI with AntiCancer's green fluorescent protein (GFP) imaging to develop non-invasive, real-time imaging for studying the effects of drugs in mouse models of cancer. The GFP gene is cloned...
07:00 , May 13, 2002 |  BC Week In Review  |  Company News

AntiCancer other research news

Researchers published in Head and Neck that HDRA was effective for in vitro drug response assessment of individual cancer patients. Tumor specimens from 41 of 42 patients undergoing treatment for head and neck cancer were...
07:00 , Aug 13, 2001 |  BC Week In Review  |  Company News

AntiCancer other research news

AntiCancer said data published in the Proceedings of the National Academy of Sciences showed that its green fluorescent protein (GFP) technology could be used for whole body imaging to visualize the infection process in mice...