23:09 , May 8, 2019 |  BC Extra  |  Company News

Management tracks: Immunocore, Kyn, Engitix

Immunocore Ltd. (Abingdon, U.K.) brought on a third ex-AstraZeneca plc (LSE:AZN; NYSE:AZN) executive, hiring Mohammed Dar as head of clinical development and CMO. Dar was VP, clinical development oncology, R&D at AZ's MedImmune LLC subsidiary....
12:56 , Apr 30, 2019 |  BC Innovations  |  Distillery Therapeutics

Syntrix's dual CXCR1/CXCR2 inhibitor for combos in oral, lung cancers

DISEASE CATEGORY: Cancer INDICATION: Lung cancer; solid tumors Mouse studies suggest combining the dual CXCR1/CXCR2 inhibitor SX-682 with anti-PD-1 mAbs or T cell therapies could help treat oral and lung cancers. In mouse models of...
19:16 , Apr 26, 2019 |  BioCentury  |  Product Development

For patients’ sake, collaborate already

Cancer immunotherapy companies must stop squandering the most precious stakeholder, patients, and collaborate now on platform trials to test new combination regimens. A straightforward platform trial design that tests different combo partners with PD-1/PD-L1 agents...
21:21 , Mar 22, 2019 |  BioCentury  |  Regulation

Manufacturing new modalities

Cell and gene therapies won’t enter the mainstream of medicine until manufacturing processes become far more efficient, according to FDA Commissioner Scott Gottlieb and FDA Center for Biologics Evaluation and Research Director Peter Marks. The...
20:04 , Mar 6, 2019 |  BC Extra  |  Company News

Judge grants Genentech some relief as JHL trade secret case moves forward

A federal judge ruled in Genentech's favor on multiple issues in its civil suit against Taiwanese company JHL Biotech, but declined to halt JHL's biosimilars development. Judge William Alsup's order was unsealed late Tuesday, following...
19:01 , Feb 22, 2019 |  BC Week In Review  |  Company News

Judge skeptical of JHL's defense in Genentech case

U.S. District Judge William Alsup met with skepticism arguments made by lawyers for JHL Biotech Inc. (Zhubei, Taiwan) during a motion hearing Feb. 14 for Genentech Inc.'s civil case against the Taiwanese company. Genentech filed...
01:20 , Feb 16, 2019 |  BC Extra  |  Company News

Judge skeptical of JHL's defense in Genentech case

U.S. District Judge William Alsup met with skepticism arguments made by lawyers for JHL Biotech Inc. (Zhubei, Taiwan) during a motion hearing Thursday for Genentech Inc.'s civil case against the Taiwanese company. Genentech filed the...
22:49 , Feb 1, 2019 |  BioCentury  |  Politics, Policy & Law

Trading blows over trade secrets

Roche’s Genentech Inc. unit kept an employee on the payroll in its South San Francisco office for almost a year after it discovered she was stealing trade secrets, watching as she channeled proprietary data to...
00:35 , Feb 1, 2019 |  BC Innovations  |  Tools & Techniques

TMB needs company

Tumor mutation burden is looking less like a magic bullet and more like just one of at least three variables that could jointly predict responses to checkpoint inhibitors. Combining TMB measurements with markers of T...
21:46 , Jan 17, 2019 |  BC Innovations  |  Finance

Public funding highlights

Public funding highlights Selected developments and initiatives in 4Q18 from major sources of public funding including National Institutes of Health (NIH), the U.K.’s Medical Research Council (MRC), the Innovative Medicines Initiative (IMI), the Canadian Institutes...