19:23 , Mar 8, 2019 |  BC Week In Review  |  Financial News

Erasca extends series A by $22M

Erasca raised additional funds to enable compound in-licensing and accelerate development of its Oncology Pattern Recognition Algorithm (OPRA) for discovering cancer cures. Erasca Inc. (San Diego, Calif.) raised $22 million in a series A extension,...
18:43 , Mar 8, 2019 |  BC Week In Review  |  Clinical News

Genentech's algorithm enhances accuracy of macular disease detection

Genentech Inc. said that by applying its deep learning algorithm to color fundus photographs (CFPs), it was able to detect diabetic macular edema (DME) with up to 97% accuracy. The results were published in Investigative...
14:04 , Feb 12, 2019 |  BC Innovations  |  Translation in Brief

Storm’s RNA modification software

Storm Therapeutics Ltd. has created an algorithm to extend the use of mass spectrometric data to RNA epigenetics. Making it open source, the company plans to put the algorithm in as many hands as possible...
16:03 , Feb 5, 2019 |  BC Innovations  |  Distillery Techniques

Assays and screens

TECHNOLOGY: Diagnostic assays An image-based test of cognitive function could help diagnose cognitive impairment, a sign of Alzheimer’s disease, mild cognitive impairment (MCI) and other neurological indications. The Integrative Cognition Assessment (ICA) test is delivered...
13:52 , Jan 29, 2019 |  BC Innovations  |  Distillery Techniques

Drug platforms; other

TECHNOLOGY: Antibody scaffolds; computational models A method of optimizing antibodies for broad activity against different viral strains could be used to generate antibodies to treat infections by influenza and other multi-strain viruses. The method is...
13:50 , Jan 29, 2019 |  BC Innovations  |  Distillery Techniques

Assays and screens; other

TECHNOLOGY: Diagnostic assays; computational models A machine-learning algorithm for analyzing TCRB sequences could help diagnose cancers. Generation and use of the model involves: extracting from patient tumor and normal tissue samples every possible 4-mer in...
19:35 , Jan 18, 2019 |  BioCentury  |  Emerging Company Profile

Achilles’ truncal neoantigens

Achilles Therapeutics Ltd. is developing a personalized T cell therapy that uses “truncal” neoantigens expressed in all tumor cells to drive T cells selected from tumor-infiltrating lymphocytes (TILs). Neoantigen discovery is fueling a burst of...
17:10 , Jan 16, 2019 |  BC Innovations  |  Distillery Techniques

Imaging; other

TECHNOLOGY: Other; computational models A machine-learning algorithm for analyzing digitized film images of the cervix could help diagnose cervical intraepithelial neoplasia (CIN) lesions of grade 2 or higher (CIN 2 or CIN >2), which are...
00:04 , Jan 16, 2019 |  BC Extra  |  Tools & Techniques

Researchers develop AI tool to improve screening for cervical cancer

A team from NCI and Intellectual Ventures Global Good Fund released a paper Thursday detailing an image-based, machine-learning algorithm that improves screening accuracy for precancerous cervical lesions. The tool could help reduce the incidence of...
21:41 , Jan 10, 2019 |  BC Innovations  |  Translation in Brief

Guided design for CRISPR editing

Separate teams from the Wellcome Sanger Institute and The Francis Crick Institute have developed an algorithm and identified a set of genetic features, respectively, that could help drug developers improve the safety of CRISPR-Cas9-based therapies...