23:28 , Oct 3, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Parkinson’s disease (PD) Cell culture and rat studies identified a positive allosteric modulator (PAM) of mGluR4 that could help treat catalepsy in PD. Optimization and testing in human mGluR4-expressing CHO cells of a previously...
18:32 , Apr 3, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Rett syndrome Patient sample and mouse studies suggest positive allosteric modulators (PAMs) of CHRM4 could help treat Rett syndrome. In postmortem cerebellum tissue samples from Rett syndrome patients, levels of CHRM4 were lower than...
15:14 , Mar 30, 2018 |  BC Week In Review  |  Financial News

Addex raises $43M

Addex Therapeutics Ltd. (SIX:ADXN) raised CHF41 million ($43 million) on March 29 through the sale of 13 million shares at CHF3.13 to New Enterprise Associates, New Leaf Venture Partners, CAM Capital and clients of Semper...
18:01 , Mar 29, 2018 |  BC Extra  |  Financial News

Addex raises $43M

Addex Therapeutics Ltd. (SIX:ADXN) raised CHF41 million ($43 million) Thursday through the sale of 13 million shares at CHF3.13 to New Enterprise Associates, New Leaf Venture Partners, CAM Capital and clients of Semper Finance Group...
15:24 , Feb 23, 2018 |  BC Week In Review  |  Financial News

Addex proposes CHF40M private placement

Neurology company Addex Therapeutics Ltd. (SIX:ADXN) proposed on Feb. 15 to raise up to CHF40 million ($42.7 million) through the sale of 12.8 million shares at CHF3.43 in a private placement. The company said CHF30...
00:20 , Feb 17, 2018 |  BC Extra  |  Financial News

Addex proposes CHF40M private placement

Addex Therapeutics Ltd. (SIX:ADXN) proposed Thursday to raise up to CHF40 million ($42.7 million) through the sale of 12.8 million shares at CHF3.43 in a private placement. The company said CHF30 million of the offering...
22:03 , Sep 18, 2017 |  BC Extra  |  Company News

Management tracks: Kamada, Vertex, Addex, Achillion

Orphan disease company Kamada Ltd. (Tel Aviv:KMDA; NASDAQ:KMDA) said Deputy CEO and CFO Gil Efron will leave at the end of the year. Chaime Orlev will become CFO, effective Jan. 1, 2018. Orlev was CFO...
20:45 , Sep 14, 2017 |  BC Innovations  |  Translation in Brief

Tracking TrkB agonists

It turns out that neurotrophic TrkB agonists used in many publications aren't TrkB agonists after all, according to a recent Science Signaling paper from Columbia University and the Broad Institute of MIT and Harvard ....
20:34 , May 23, 2017 |  BC Innovations  |  Distillery Techniques

Drug delivery; drug platforms

TECHNOLOGY: Other; conjugates A method of generating photosensitive prodrugs could enable site-specific activation of therapies for neurological and other diseases. The prodrugs consisting of pain signaling inhibitors conjugated to a violet light-absorbing coumarin analog released...
04:42 , Mar 3, 2017 |  BC Week In Review  |  Financial News

Addex Therapeutics completes private placement

On Feb. 28, neurology company Addex Therapeutics Ltd. (SIX:ADXN) raised CHF3 million ($3 million) through the sale of 1.5 million treasury shares at CHF2 in a private placement led by Herculis Partners. Addex Therapeutics Ltd....