22:06 , May 11, 2017 |  BC Innovations  |  Tools & Techniques

Stemming the tide

OncoMed’s bad April has all the hallmarks of a death knell for the once-promising technology of cancer stem cells, adding to the pile of preclinical breakthroughs that didn’t translate to the clinic. But many insiders...
07:00 , Sep 10, 2012 |  BioCentury  |  Emerging Company Profile

Stem Cell Differentiator

While most companies working on cancer stem cells appear to be developing compounds to kill the cells themselves, Actium Research Inc. is working on ways to make these cells vulnerable to chemotherapy. The company's screening...
07:00 , Aug 16, 2012 |  BC Innovations  |  Cover Story

Tracing cancer stem cells

Three academic teams have independently developed techniques for in vivo detection of cancer stem cells in mouse solid tumors.1-3 The methods could be useful as next-generation target discovery platforms and as screens for compounds that...
07:00 , Jul 19, 2012 |  BC Innovations  |  Targets & Mechanisms

OutFOXing tumors

A Mount Sinai School of Medicine and Case Western Reserve University team has found a new use for the dopamine receptor antagonist trifluoperazine: restoring the sensitivity of tumors to epidermal growth factor receptor inhibitors.1 The...