22:04 , Jan 8, 2019 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Melanoma Mouse studies suggest PPARα agonists could enhance the efficacy of adoptive T cell therapies for melanoma. In a mouse model of melanoma, adoptive transfer of CD8 + T cells pretreated with a tool...
23:48 , Oct 15, 2018 |  BC Extra  |  Company News

Management tracks: Rhythm, Redpin

Rhythm Pharmaceuticals Inc. (NASDAQ:RYTM) hired Murray Stewart as CMO of the metabolic disorder company. Stewart was CMO of GlaxoSmithKline plc (LSE:GSK; NYSE:GSK) until 2017 when he became head of R&D at Novelion Therapeutics Inc. (NASDAQ:NVLN)....
17:52 , Aug 29, 2018 |  BC Innovations  |  Distillery Therapeutics

Infectious disease

INDICATION: Sepsis Cell culture and mouse studies identified a GSDMD inhibitor that could help treat sepsis. In vitro , the previously identified necroptosis inhibitor necrosulfamide bound GSDMD with a K d of 32 μM. In...
00:06 , Mar 3, 2018 |  BC Extra  |  Politics & Policy

Senator questions pharmas on use of tax savings

Sen. Tina Smith (D-Minn.) sent letters to the CEOs of five large U.S. pharmas on Thursday questioning how they have been using their corporate tax savings since the passage of the Tax Cuts and Jobs...
20:46 , Feb 16, 2018 |  BC Week In Review  |  Clinical News

Priority Review for Agios' ivosidenib

Agios Pharmaceuticals Inc. (NASDAQ:AGIO) said FDA accepted and granted Priority Review to an NDA for ivosidenib (AG-120) to treat relapsed or refractory acute myelogenous leukemia (AML) in patients with an isocitrate dehydrogenase 1 (IDH1) mutation....
19:38 , Feb 16, 2018 |  BC Week In Review  |  Clinical News

FDA approves Banyan's brain trauma blood test

FDA approved the Banyan Brain Trauma Indicator (BTI) from Banyan Biomarkers Inc. (Alachua, Fla.) as an in vitro diagnostic blood test to aid in the evaluation of adults with suspected mild traumatic brain injury (TBI)....
19:45 , Feb 15, 2018 |  BC Extra  |  Company News

Priority Review for Agios' ivosidenib

Agios Pharmaceuticals Inc. (NASDAQ:AGIO) said FDA accepted and granted Priority Review to an NDA for ivosidenib (AG-120) to treat relapsed or refractory acute myelogenous leukemia (AML) in patients with an isocitrate dehydrogenase 1 (IDH1) mutation....
22:50 , Jan 19, 2018 |  BioCentury  |  Finance

Earnings on deck

Earnings on deck At least seven profitable biotechs and pharmas are slated to report earnings this week. (A) Premarket on U.S. exchanges, during trading hours in Europe; (B) Fiscal 3Q Company Date Pre/post mkt 4Q17...
23:36 , Jan 17, 2018 |  BC Extra  |  Company News

Management tracks: NanoString, Orchard

Molecular diagnostics company NanoString Technologies Inc. (NASDAQ:NSTG) hired Thomas Bailey as CFO. He was CFO of AgaMatrix Holdings LLC (Salem, N.H.). Gene therapy company Orchard Therapeutics Ltd. (London, U.K.) hired Frank Thomas as CFO and...
22:32 , Dec 18, 2017 |  BC Extra  |  Company News

China's RDPAC names executive committee

China's R&D-based Pharmaceutical Association Committee, a non-profit organization made up of 41 multinational biopharmaceutical companies, named 13 members to its 2018-19 executive committee. Appointees include Jean-Christophe Pointeau as chairman and Hong Chow, Renaud Gabay and...