23:23 , Mar 27, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Multiple myeloma (MM) Patient sample and mouse studies suggest inhibiting IL-18 or NLRP1 could help treat MM. In patient samples, high bone marrow plasma levels of IL-18 correlated with poor overall survival. In two...
19:23 , Jan 17, 2018 |  BC Innovations  |  Distillery Therapeutics

Cancer

INDICATION: Gastric cancer Patient sample and mouse studies suggest inhibiting PYCARD or its downstream effector IL-18 could help treat gastric cancer. In tumor samples from patients, levels of PYCARD and IL-18 were higher than in...
08:00 , Jan 18, 2016 |  BC Week In Review  |  Financial News

AB2 Bio completes venture financing

AB2 Bio Ltd. , Lausanne, Switzerland   Business: Inflammation   Date completed: 2016-01-11   Type: Venture financing   Raised: CHF21 million ($21.1 million)   Investors: Existing investors; new investors  ...
08:00 , Nov 16, 2015 |  BC Week In Review  |  Clinical News

IL-18BP: Compassionate use program data

AB2 said a 3-month old girl with macrophage activation syndrome due to a genetic mutation of the NRL family CARD domain containing 4 (NLRC4) gene was in full remission after receiving 3 months of treatment...