BC Innovations | Apr 4, 2017
Distillery Techniques

Imaging

TECHNOLOGY: Other A light-scattering spectroscopic method could aid the differential diagnosis of benign and precancerous pancreatic cysts. The method involves guiding a fiber optic-based, light-scattering spectroscopic probe to the internal surfaces of pancreatic cysts during...
BC Innovations | Aug 14, 2014
Cover Story

Navigating the new road in psychiatry

The lack of predictive animal models for neuropsychiatric diseases is arguably the biggest single factor stifling drug development in the field. To kick-start discovery for diseases such as autism, schizophrenia and depression, stakeholders will need...
BC Innovations | Aug 7, 2014
Tools & Techniques

High throughput remyelination

Remyelinating compounds are highly sought after but have been difficult to identify in part because there is a dearth of high throughput screening platforms to detect remyelination. Researchers at the University of California, San Francisco...
BC Innovations | Jul 17, 2014
Targets & Mechanisms

Hedgehog joins the resistance

Increased glucuronidation by activated hedgehog signaling turns out to be the root of drug resistance for at least two compounds in acute myeloid leukemia. 1 Inhibiting the pathway could avoid the toxicity of general glucuronidase...
BC Innovations | Jul 10, 2014
Targets & Mechanisms

Priming the PD pump

The precise cause of neurodegeneration in Parkinson's disease remains unknown, and as a result no one has been able to develop a truly disease-modifying therapy. Now, independent teams in Europe and the U.S. have found...
BioCentury | Jun 30, 2014
Emerging Company Profile

Inception 5: Myelin layer

Inception 5 Inc. is among a handful of companies pursuing the next frontier of multiple sclerosis treatments - compounds that induce remyelination. The company is using a screening platform to discover small molecules that could have...
BC Innovations | Jun 19, 2014
Translation in Brief

Translational tidbits

Autism Speaks to Google Patient advocacy group BGI and its subsidiary Complete Genomics Inc. Although obtaining genomic sequences proved relatively cheap and easy, making sense of the sequences proved technically challenging because of the vast...
BC Innovations | Jun 12, 2014
Targets & Mechanisms

Putting SMYD3 on the MAP

Stanford University and GlaxoSmithKline plc researchers have uncovered the mechanism of action of SMYD3 , a histone lysine methyltransferase overexpressed in many lung and pancreatic tumors. 1 The surprise was that SMYD3 acts in the cytoplasm...
BioCentury | Jun 9, 2014
Emerging Company Profile

Glactone: ProSTATe stopper

Glactone Pharma AB is developing small molecule inhibitors of a mitogenic transcription factor that is overactive in castration-resistant prostate cancer and other solid tumors. The company has mechanistic evidence that its derivatives of the fungal...
BC Innovations | May 22, 2014
Translation in Brief

Translational tidbits

Berg's big data dive Berg Pharma LLC is seeking to validate its Interrogative Biology toolkit by striking academic partnerships with the University of Miami Miller School of Medicine and Medical University of South Carolina . Berg...
Items per page:
1 - 10 of 371
BC Innovations | Apr 4, 2017
Distillery Techniques

Imaging

TECHNOLOGY: Other A light-scattering spectroscopic method could aid the differential diagnosis of benign and precancerous pancreatic cysts. The method involves guiding a fiber optic-based, light-scattering spectroscopic probe to the internal surfaces of pancreatic cysts during...
BC Innovations | Aug 14, 2014
Cover Story

Navigating the new road in psychiatry

The lack of predictive animal models for neuropsychiatric diseases is arguably the biggest single factor stifling drug development in the field. To kick-start discovery for diseases such as autism, schizophrenia and depression, stakeholders will need...
BC Innovations | Aug 7, 2014
Tools & Techniques

High throughput remyelination

Remyelinating compounds are highly sought after but have been difficult to identify in part because there is a dearth of high throughput screening platforms to detect remyelination. Researchers at the University of California, San Francisco...
BC Innovations | Jul 17, 2014
Targets & Mechanisms

Hedgehog joins the resistance

Increased glucuronidation by activated hedgehog signaling turns out to be the root of drug resistance for at least two compounds in acute myeloid leukemia. 1 Inhibiting the pathway could avoid the toxicity of general glucuronidase...
BC Innovations | Jul 10, 2014
Targets & Mechanisms

Priming the PD pump

The precise cause of neurodegeneration in Parkinson's disease remains unknown, and as a result no one has been able to develop a truly disease-modifying therapy. Now, independent teams in Europe and the U.S. have found...
BioCentury | Jun 30, 2014
Emerging Company Profile

Inception 5: Myelin layer

Inception 5 Inc. is among a handful of companies pursuing the next frontier of multiple sclerosis treatments - compounds that induce remyelination. The company is using a screening platform to discover small molecules that could have...
BC Innovations | Jun 19, 2014
Translation in Brief

Translational tidbits

Autism Speaks to Google Patient advocacy group BGI and its subsidiary Complete Genomics Inc. Although obtaining genomic sequences proved relatively cheap and easy, making sense of the sequences proved technically challenging because of the vast...
BC Innovations | Jun 12, 2014
Targets & Mechanisms

Putting SMYD3 on the MAP

Stanford University and GlaxoSmithKline plc researchers have uncovered the mechanism of action of SMYD3 , a histone lysine methyltransferase overexpressed in many lung and pancreatic tumors. 1 The surprise was that SMYD3 acts in the cytoplasm...
BioCentury | Jun 9, 2014
Emerging Company Profile

Glactone: ProSTATe stopper

Glactone Pharma AB is developing small molecule inhibitors of a mitogenic transcription factor that is overactive in castration-resistant prostate cancer and other solid tumors. The company has mechanistic evidence that its derivatives of the fungal...
BC Innovations | May 22, 2014
Translation in Brief

Translational tidbits

Berg's big data dive Berg Pharma LLC is seeking to validate its Interrogative Biology toolkit by striking academic partnerships with the University of Miami Miller School of Medicine and Medical University of South Carolina . Berg...
Items per page:
1 - 10 of 371