20:03 , Mar 1, 2019 |  BC Week In Review  |  Company News

Spark gives Roche beachhead in gene therapy

Roche (SIX:ROG; OTCQX:RHHBY) will acquire Spark Therapeutics Inc. (NASDAQ:ONCE) for $4.8 billion in a deal that marks the Swiss pharma's first major move into gene therapy. The deal announced early Feb. 25 was the first...
07:11 , Feb 25, 2019 |  BC Extra  |  Company News

Spark gives Roche beachhead in gene therapy

Roche (SIX:ROG; OTCQX:RHHBY) will acquire Spark Therapeutics Inc. (NASDAQ:ONCE) for $4.8 billion in a deal that marks the Swiss pharma's first major move into gene therapy. The deal announced early Monday was the first major...
00:10 , Feb 20, 2019 |  BC Extra  |  Company News

Management tracks: Allergan, Arix, Quest, SurModics

Allergan plc (NYSE:AGN) appointed Robert Hugin to its board. He stepped down as CEO of Celgene Corp. (NASDAQ: CELG) in 2016, and retired as Celgene's executive chairman last year. Mark Alles is Celgene's current chairman...
02:37 , Sep 14, 2018 |  BC Innovations  |  Product R&D

Academia’s manufacturing problem

With backups at academic manufacturing centers beginning to hamper translation of early stage gene therapies, pushing those who can afford it to CMOs, at least one non-profit has stepped in with a model to deliver...
18:39 , Sep 7, 2018 |  BC Week In Review  |  Financial News

4D Molecular rises $90M series B

Gene therapy company 4D Molecular Therapeutics Inc. (Emeryville, Calif.) raised $90 million on Sept. 5 in an untranched series B round led by new investor Viking Global Investors. Fellow new investors ArrowMark Partners, Janus Henderson...
12:01 , Sep 5, 2018 |  BC Extra  |  Financial News

4D Molecular raises $90M series B

Gene therapy company 4D Molecular Therapeutics Inc. (Emeryville, Calif.) raised $90 million in an untranched series B round led by new investor Viking Global Investors. Fellow new investors ArrowMark Partners, Janus Henderson Investors, The Biotechnology...
22:30 , Feb 2, 2018 |  BioCentury  |  Product Development

AA Viral meme

Gene therapy pioneer James Wilson’s revelation of two new types of toxicity in animals receiving high systemic doses of adeno-associated viral vectors is unlikely to herald a major disruption of the AAV space, though it...
19:31 , Jan 17, 2018 |  BC Innovations  |  Distillery Therapeutics

Neurology

INDICATION: Amyotrophic lateral sclerosis (ALS) Mouse studies suggest a CRISPR/Cas9-based system that inhibits SOD1 in the CNS could help treat ALS. In a transgenic mouse model of ALS expressing mutant human SOD1, IV injection of...
01:15 , Dec 13, 2016 |  BC Extra  |  Financial News

Pfizer invests in cancer newco Ignite

Pfizer Inc. (NYSE:PFE) invested an undisclosed amount to take a 50% stake in newly launched Ignite Immunotherapy Inc. (Alameda, Calif.). Ignite also announced a strategic collaboration in which Pfizer is to provide R&D funding for...
07:00 , Aug 1, 2016 |  BC Extra  |  Company News

Pfizer acquires gene therapy company Bamboo

Pfizer Inc. (NYSE:PFE) acquired the 78% of Bamboo Therapeutics Inc. (Chapel Hill, N.C.) it did not already own for $150 million up front and $495 million in milestones. In 1Q16, the pharma obtained a 22%...